Is breast cancer survival improving

摘要: BACKGROUND Despite advances in therapies for breast cancer, improvement survival patients with recurrent or metastatic cancer has been difficult to establish. The objective of the current study was determine whether women improved from 1974 2000. METHODS The authors analyzed experience 834 who developed between November and December 2000. All had treated previously adjuvant anthracycline-based protocols. Patients were divided into five consecutive groups based on year recurrence, compared across groups. Because some prognostic variables unevenly among cohorts, a multivariate model created association recurrence after accounting other factors. RESULTS In unadjusted analysis, there statistically significant groups, more recent cohorts longer (P < 0.001). Other that predicted included smaller initial tumor size, lower stage disease, fewer lymph nodes involved, disease-free interval, estrogen receptor–positive tumors, nonvisceral dominant site disease recurrence. In which adjusted these factors, associated trend toward survival, 1% reduction risk each increasing year. CONCLUSIONS For patients, present data suggesting prognosis Cancer 2004;100:44–52. © 2003 American Society.