Colonization with group B streptococci in pregnancy and adverse outcome
作者： Joan A Regan , Mark A Klebanoff , Robert P Nugent , David A Eschenbach , William C Blackwelder
DOI: 10.1016/S0002-9378(96)70684-1
关键词: Odds ratio 、 Medicine 、 Neonatal sepsis 、 Gestation 、 Risk factor 、 Low birth weight 、 Group B 、 Obstetrics 、 Sepsis 、 Pregnancy
摘要: Abstract OBJECTIVE: Our purpose was to study the association of cervicovaginal colonization with group B streptococci pregnancy and neonatal outcome. STUDY DESIGN: A prospective conducted at seven medical centers between 1984 1989. Genital tract cultures were obtained 23 26 weeks' gestation delivery. Prematurity sepsis rates compared positive negative women. RESULTS: Group recovered from 2877 (21%) 13,646 women enrollment. Heavy associated a significant risk delivering preterm infant who had low birth weight (odds ratio=1.5, 95% confidence interval 1.1 1.9). Heavily colonized given antibiotics effective against little increased preterm, low-birth-weight birth. Women light same adverse outcome as uncolonized Neonatal occurred in 2.6 1000 live births 1.6 without ( p = 0.11). However, 16 0.4 delivery CONCLUSIONS: an infant. Cervicovaginal not reliable predictor sepsis. Colonization (AM J OBSTET GYNECOL 1996;174:1354-60.)
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