B-cell targeting in rheumatoid arthritis and other autoimmune diseases.

作者: Jonathan C. W. Edwards , Geraldine Cambridge

DOI: 10.1038/NRI1838

关键词: ImmunologyRituximabAutoimmune diseaseMonoclonal antibodyDiseaseRheumatoid arthritisPeripheral bloodMedicineArthritisB cell

摘要: … This Review focuses on B-cell targeting in rheumatoid arthritis but also describes the progress of B-cell targeting strategies in other human diseases, as well as probable future research …

参考文章(97)
Jonathan C. W. Edwards, Geraldine Cambridge, Maria J. Leandro, B Lymphocyte Depletion Therapy in Autoimmune Disorders: Chasing Trojan Horses In: Molecular Autoimmunity. (pp. 291-311). (2005). pp. 291- 311 ,(2005) , 10.1007/0-387-24534-0_21
Jonathan CW Edwards, Fibroblast biology Development and differentiation of synovial fibroblasts in arthritis Arthritis Research & Therapy. ,vol. 2, pp. 344- 347 ,(2000) , 10.1186/AR110
Mark S Cragg, Claire A Walshe, Andrey O Ivanov, Martin J Glennie, None, The biology of CD20 and its potential as a target for mAb therapy. Current directions in autoimmunity. ,vol. 8, pp. 140- 174 ,(2005) , 10.1159/000082102
Fabienne Mackay, Frederic Sierro, Shane T. Grey, Tom P. Gordon, The BAFF/APRIL system: an important player in systemic rheumatic diseases. Current directions in autoimmunity. ,vol. 8, pp. 243- 265 ,(2005) , 10.1159/000082106
Anne-Sophie Rouzière, Christian Kneitz, Arumugam Palanichamy, Thomas Dörner, Hans-Peter Tony, Regeneration of the immunoglobulin heavy-chain repertoire after transient B-cell depletion with an anti-CD20 antibody Arthritis Research & Therapy. ,vol. 7, pp. 1- 11 ,(2005) , 10.1186/AR1731
M.J. Arin, A. Engert, T. Krieg, N. Hunzelmann, Anti‐CD20 monoclonal antibody (rituximab) in the treatment of pemphigus British Journal of Dermatology. ,vol. 153, pp. 620- 625 ,(2005) , 10.1111/J.1365-2133.2005.06651.X
Jane A. Gross, Janet Johnston, Sherri Mudri, Rachel Enselman, Stacey R. Dillon, Karen Madden, Wenfeng Xu, Julia Parrish-Novak, Don Foster, Cathy Lofton-Day, Margaret Moore, Alisa Littau, Angelika Grossman, Harald Haugen, Kevin Foley, Hal Blumberg, Kim Harrison, Wayne Kindsvogel, Christopher H. Clegg, TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease Nature. ,vol. 404, pp. 995- 999 ,(2000) , 10.1038/35010115
Qian Gong, Qinglin Ou, Shiming Ye, Wyne P. Lee, Jennine Cornelius, Lauri Diehl, Wei Yu Lin, Zhilan Hu, Yanmei Lu, Yongmei Chen, Yan Wu, Y. Gloria Meng, Peter Gribling, Zhonghua Lin, Kathy Nguyen, Thanhvien Tran, Yifan Zhang, Hugh Rosen, Flavius Martin, Andrew C. Chan, Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy. Journal of Immunology. ,vol. 174, pp. 817- 826 ,(2005) , 10.4049/JIMMUNOL.174.2.817
Rami Kotb, Gwenola Maigne, François-Xavier Blanc, Cécile Goujard, Jean François Delfraissy, Olivier Lambotte, Efficacy of rituximab in refractory polymyositis. The Journal of Rheumatology. ,vol. 32, pp. 1369- 1370 ,(2005)