Multi-target directed donepezil-like ligands for Alzheimer's disease

作者: Mercedes Unzeta , Gerard Esteban , Irene Bolea , Wieslawa A. Fogel , Rona R. Ramsay

DOI: 10.3389/FNINS.2016.00205

关键词: DonepezilAcetylcholineButyrylcholinesteraseDementiaAcetylcholinesteraseMonoamine neurotransmitterDiseasePsychologyNeuroscienceNeuroinflammation

摘要: … In this regard Youdim and co-workers have reported a novel multifunctional molecule, M30, which combines iron-chelation with and monoamine oxidase (MAO) inhibitory properties as …

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