Stereospecific Olefin Synthesis via Lithium Vinylcuprates
作者： F. Näf , P. Degen
关键词: Stereospecificity 、 Halide 、 Olefin synthesis 、 Medicinal chemistry 、 Chemistry 、 Lithium 、 Double bond 、 Conjugate 、 Organic chemistry 、 Alkyl
摘要: The conjugate addition of cis- or trans-1-alkenyl-cuprolithium complexes (RCHCH)2CuLi · Xn1 to α, β-unsaturated carbonyl compounds was found occur with high retention double bond geometry, affording isomerically pure trans-γ, δ-ethylenic compounds. same 1-alkenylcuprates also react stereospecifically alkyl halides give trans-olefins.
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