Giant Cell Tumor of the Spine

作者: Neal Luther , Mark H. Bilsky , Roger Härtl

DOI: 10.1016/J.NEC.2007.09.009

关键词: SurgeryGross Total ResectionGiant cellRadiation therapySacrumMalignant transformationEmbolizationGiant Cell TumorsMedicineSubtotal Resection

摘要: Giant cell tumors are benign but locally aggressive neoplasms that typically affect the extremities. When involving spine, occur predominantly in sacrum. Gross total resection of tumor with wide margins yields good results terms survival. However, it carries a significant potential for morbidity and disability. Subtotal adjuvant radiation risk recurrence or, more concerning, sarcomatous malignant transformation. Endovascular embolizations have also been attempted to control unresectable tumors, performed moderate degrees success. Outcomes analyzed outcomes following surgery, therapy, embolization.

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