Facultative methanotrophy: false leads, true results, and suggestions for future research

摘要: Methanotrophs are a group of phylogenetically diverse microorganisms characterized by their ability to utilize methane as sole source carbon and energy. Early studies suggested that growth on could be stimulated with the addition some small organic acids, but initial efforts find facultative methanotrophs, i.e., methanotrophs able compounds carbon-carbon bonds substrates were inconclusive. Recently, however, in genera Methylocella, Methylocapsa, Methylocystis have been reported can grow acetate, well larger acids or ethanol for species. All identified within Alphaproteobacteria serine cycle assimilation from formaldehyde. It is possible convert acetate into intermediates (e.g. malate glyoxylate), because variety pathways these glyoxylate shunt tricarboxylic acid cycle, ethylmalonyl-CoA pathway, citramalate methylaspartate cycle). In this review, we summarize history methanotrophy, describe scenarios basis pose several topics future research area.