Effect of Size and Functionalization of Pharmaceutical Nanoparticles and Their Interaction with Biological Systems

摘要: This work reflects the need to have information on physicochemical properties of pharmaceutical nanoparticles and their interaction with biological systems, especially like particle size surface functionalization that give special features when go through membranes, during opsonization, against immunogenicity, different toxicities, etc. aims help new researchers better understand close relationship between effects systems also contribute nanotechnologists take into account this situation be aware responsibility does not end development manufacture these nanosystems. chapter was written for specialist in areas enrich its content, it is vision a single author. We collaborated document nanotechnologists, toxicologists, technologists critical approach imminent progress nanotechnology many knowledge such as pharmaceuticals, cosmetics, foods, chemical industry, computer Interaction human tissues, plants, animals, soils, water, air, inevitable because future, will an important source pollution we must know how they interact surroundings depending properties. Currently, branch Nanotechnology called Nanotoxicology has been developed deal dilemmas future much more than nowadays. Standardized protocols established evaluate cytotoxicity genotoxicity caused by nanostructures.