Nocturnal polyuria in type 2 diabetes: a symptom of obstructive sleep apnea.

作者: Eileen R. Chasens , Mary Q. Umlauf , Dennis J. Pillion , Judy A. Wells

DOI: 10.1177/014572170202800312

关键词: Internal medicineType 2 diabetesDiabetes mellitusObstructive sleep apneaUrineNocturiaEndocrinologyMedicineSleep apneaRenal thresholdPolysomnography

摘要: PURPOSEPolyuria and nocturia in individuals with type 2 diabetes may be due to obstructive sleep apnea (OSA), a recently recognized etiology of excess nighttime urine production. This exploratory study examined the relationships among glucose control, OSA, nocturnal production.METHODSA sample community-dwelling older adults (20 nondiabetic subjects 10 poorly controlled subjects) was recruited based on self-report more than twice per night. Participants were monitored metabolic research unit for 24 hours track intake/output, collect blood samples, conduct an overnight polysomnography study.RESULTSNone had fasting serum levels above renal threshold. OSA found 65% subjects. Those moderate/severe significantly greater production without OSA. Subjects highest production.CONCLUSIONSThe high i...

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