Label Propagation Prediction of Drug-Drug Interactions Based on Clinical Side Effects

作者: Ping Zhang , Fei Wang , Jianying Hu , Robert Sorrentino

DOI: 10.1038/SREP12339

关键词: Drug labelingMachine learningPubChemPackage insertPredictive medicineAdverse Event Reporting SystemComputational modelClinical trialMedical prescriptionArtificial intelligenceDrugComputer science

摘要: Drug-drug interaction (DDI) is an important topic for public health and thus attracts attention from both academia and industry. Here we hypothesize that clinical side effects (SEs) …

参考文章(32)
Jesse Davis, Mark Goadrich, The relationship between Precision-Recall and ROC curves Proceedings of the 23rd international conference on Machine learning - ICML '06. ,vol. 148, pp. 233- 240 ,(2006) , 10.1145/1143844.1143874
John Duchi, Shai Shalev-Shwartz, Yoram Singer, Tushar Chandra, Efficient projections onto thel1-ball for learning in high dimensions Proceedings of the 25th international conference on Machine learning - ICML '08. pp. 272- 279 ,(2008) , 10.1145/1390156.1390191
Zhichao Liu, Qiang Shi, Don Ding, Reagan Kelly, Hong Fang, Weida Tong, Translating Clinical Findings into Knowledge in Drug Safety Evaluation - Drug Induced Liver Injury Prediction System (DILIps) PLoS Computational Biology. ,vol. 7, pp. e1002310- ,(2011) , 10.1371/JOURNAL.PCBI.1002310
Masataka Takarabe, Daichi Shigemizu, Masaaki Kotera, Susumu Goto, Minoru Kanehisa, Network-based analysis and characterization of adverse drug-drug interactions. Journal of Chemical Information and Modeling. ,vol. 51, pp. 2977- 2985 ,(2011) , 10.1021/CI200367W
Michael Kuhn, Damian Szklarczyk, Andrea Franceschini, Monica Campillos, Christian von Mering, Lars Juhl Jensen, Andreas Beyer, Peer Bork, STITCH 2: an interaction network database for small molecules and proteins Nucleic Acids Research. ,vol. 38, pp. 552- 556 ,(2010) , 10.1093/NAR/GKP937
Santiago Vilar, Eugenio Uriarte, Lourdes Santana, Nicholas P. Tatonetti, Carol Friedman, Detection of Drug-Drug Interactions by Modeling Interaction Profile Fingerprints PLOS ONE. ,vol. 8, pp. 1- 11 ,(2013) , 10.1371/JOURNAL.PONE.0058321
Lun Yang, Pankaj Agarwal, Systematic Drug Repositioning Based on Clinical Side-Effects PLoS ONE. ,vol. 6, pp. e28025- ,(2011) , 10.1371/JOURNAL.PONE.0028025
Linna He, Zhihao Yang, Zhehuan Zhao, Hongfei Lin, Yanpeng Li, Extracting Drug-Drug Interaction from the Biomedical Literature Using a Stacked Generalization-Based Approach PLoS ONE. ,vol. 8, pp. e65814- ,(2013) , 10.1371/JOURNAL.PONE.0065814
Abhinita Subhadarshini, Shreyas D. Karnik, Xiaochun Li, Stephen D. Hall, Yan Jin, J. Thomas Callaghan, Marcus J. Overhage, David A. Flockhart, R. Matthew Strother, Sara K. Quinney, Lang Li, Jon D. Duke, Xu Han, Zhiping Wang, Literature Based Drug Interaction Prediction with Clinical Assessment Using Electronic Medical Records: Novel Myopathy Associated Drug Interactions PLoS Computational Biology. ,vol. 8, pp. e1002614- ,(2012) , 10.1371/JOURNAL.PCBI.1002614
Sonja Gandhi, Muhammad Mamdani, Tara Gomes, Jamie Fleet, Y. Joseph Hwang, Amit X. Garg, Amit M. Patel, Salimah Shariff, David G. Bailey, David N. Juurlink, Statin Toxicity From Macrolide Antibiotic Coprescription: A Population-Based Cohort Study Annals of Internal Medicine. ,vol. 158, pp. 869- 876 ,(2013) , 10.7326/0003-4819-158-12-201306180-00004