Prognostic Utility of Metabolic Exercise Testing in Minimally Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy

摘要: Patients with obstructive hypertrophic cardiomyopathy (HC) are at increased risk of death or severe symptoms. Although metabolic exercise testing is routinely used in the evaluation a variety cardiac diseases, data on prognostic information that can be derived from such HC lacking. We examined 182 patients (mean age 53 ± 15 years; 65% men) and minimal no cardiovascular Each patient underwent maximum simultaneous gas exchange measurement. Follow-up 4.0 3.0 100% complete) was performed to determine vital status occurrence symptoms, defined as class III IV symptoms dyspnea angina. Multiple parameters were associated development On multivariate analyses, independent predictors severity left ventricular outflow tract gradient rest percentage predicted peak myocardial oxygen consumption achieved during exercise. For <60%, 4-year survival rate free only 59%. In conclusion, among mild low capacity an subsequent