Disconnected pancreatic duct syndrome in severe acute pancreatitis: clinical and imaging characteristics and outcomes in a cohort of 31 cases.

摘要: Results: The median patient age was 53 years (range 20-83 years); 48% were men. most common etiology of acute pancreatitis (AP) biliary (55%) followed by idiopathic (27%). interval between the diagnoses AP and DPDS 56 days 3-251 days); follow-up after last ERCP or surgical procedure 7 months 0-90 months). location included following: pancreas head 6%, neck 58%, body 26%, tail 10%. Twenty-six patients had initial endoscopic treatment (19 long-term improvement; failed required surgery) 5 underwent immediate surgery. Mortality 0%; 26% developed chronic (CP) 16% diabetes mellitus (DM); 10% resolved completely, 45% smaller fluid collections, lost to follow-up. No relationship demographic clinical data with outcomes found. Conclusions: Endoscopic temporarily improved DPDS, a failure rate 23%. Immediate surgery not in all cases. CP and/or pancreatic atrophy occurred relatively shortly diagnosis DM did lead mortality. Early may be considered initially stabilizing collection therapy. (Gastrointest Endosc 2008;68:91-7.)