作者: Claudia Yvonne Janda , Kenan Christopher Garcia , Luke Dang , David Baker , James Daniel Moody
DOI:
关键词: Wnt signaling pathway 、 Chemistry 、 LRP6 、 Frizzled 、 Agonist 、 Cell biology 、 LRP5 、 Moiety 、 Molecule 、 Conjugated system
摘要: Wnt signaling agonist compositions and methods for their use are provided. agonists of the invention comprise a frizzled binding moiety, which is fused or conjugated to an LRP5 LRP6 moiety.