作者: Jean Boucher , Linnea Olson , Bilal Piperdi
关键词: Discontinuation 、 Intensive care medicine 、 Epidermal Growth Factor Receptor Inhibitors 、 Quality of life 、 Medicine 、 EGF Signaling Pathway 、 Head and neck 、 Patient support 、 Treatment options 、 Treatment regimen
摘要: Epidermal growth factor receptor inhibitors (EGFRIs) are a treatment option for patients diagnosed with advanced-stage gastrointestinal, lung, and head neck cancers. The most prevalent complications associated EGFRIs dermatologic toxicities, which may result in either disruption or discontinuation of adversely affect patients' quality life. Nurses play vital role educating about EGFRI-related toxicities; therefore, nurses must continue to educate themselves on the various aspects EGFRI treatment. An overview EGF signaling pathway is provided, toxicities described. A review several studies evaluating reactive skin regimens also discussed. critical providing patient support. Informing potential symptoms will help prepare their course In addition, should provide variety coping strategies manage that assist enhancing adherence