Use of retinoids plus histone deacetylase inhibitors to inhibit the growth of solid tumors

作者: Lorraine J. Gudas , David Nanus

DOI:

关键词: Cancer researchTrichostatin AKidneyProstateHistone deacetylase inhibitorLungHistone deacetylasePancreasPathologyRetinoidBiology

摘要: The present invention provides a method of inhibiting growth solid tumors in an animal which comprises administering effective amount trichostatin A (TSA) to need such treatment. also histone deacetylase inhibitor and retinoid Examples may be treated using the methods include but are not limited carcinomas head neck, breast, skin, kidney, oral cavity, colon, prostate, pancreas lung.

参考文章(1)
Pier Paolo Pandolfi, Transcription therapy for cancer Oncogene. ,vol. 20, pp. 3116- 3127 ,(2001) , 10.1038/SJ.ONC.1204299