Pharmaceutically acceptable composition comprising an aqueous solution of paclitaxel and albumin

作者: Krisztina Krempels , Robert C. Tuttle , Tenshuk A. Kadima , Lajos Hegedus , Howard A. Kaplan

DOI:

关键词: PaclitaxelOrganic solventChromatographyMaterials scienceSerum albuminAlbuminAqueous solutionComposition (visual arts)

摘要: An optically clear, pharmaceutically acceptable aqueous composition comprising paclitaxel or a derivative thereof, serum albumin and vehicle, wherein the comprises no more than 10 % organic solvent has pH of about 3.0 to 4.8, is described. The can be fatted defatted, optionally lyophilized reconstituted. At least 70 bound albumin, ratio at 1:5, concentration 25 νg/ml. Methods making using this are also provided.

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