Processing cartridge and method for detecting a pathogen in a sample

作者: Eric Schneider , Scott Corey , David Walter Wright , Dominic Aiello , Jay Srinivasan

DOI:

关键词: Mixing (process engineering)ElectrowettingAcousticsSample (graphics)CartridgeMaterials science

摘要: In one embodiment, a multiplex fluid processing cartridge includes sample well, deformable chamber, mixing well with mixer disposed therein, lysis chamber including mixer, an electrowetting grid for microdroplet manipulation, and electrosensor arrays configured to detect analytes of interest. An instrument the is receive selectively apply thermal energy, magnetic force, electrical connections or more discrete locations on further compress chamber(s) in specified sequence.

参考文章(473)
John T. Mcdevitt, Glennon W. Simmons, Karri Ballard, Nicolaos J. Christodoulides, Pierre N. Floriano, Systems and methods including self-contained cartridges with detection systems and fluid delivery systems ,(2006)
Fredrick Michael Coory, Discharge cap with releasable tablet basket ,(1998)
John P. O'Daly, Marek Wojciechowski, Junguo Zhao, Steven Wegner, Terence M. McCaffrey, Michael A. Harpold, Robert W. Henkens, Najih Naser, Susan E. Morris, Colloidal-gold electrosensor measuring device ,(1994)
Michael Riedling, Martin Mennig, Helmut Schmidt, Herbert Harttig, Magnetic particles for purifying nucleic acids ,(1999)
Khushroo Gandhi, Luc J. Bousse, Robert S. Dubrow, Methods of fabricating polymeric structures incorporating microscale fluidic elements ,(1999)
William Charles Dicke, Jason Andrew Macleod, Gordon Bruce Collier, John Allister Wood, Attila Csaba Nemeth, Cary James Miller, Nucleic acid separation and amplification ,(2010)
Weidong Cao, Kevin Louder, Hiroshi Inoue, Methods and systems for microfluidic dna sample preparation ,(2009)