Cadmium burden of men and women who report regular consumption of confectionery sunflower kernels containing a natural abundance of cadmium.

作者: P G Reeves , R A Vanderpool

DOI: 10.1289/EHP.971051098

关键词: Animal scienceSunflowerCadmiumHelianthusUrinary excretionUrineDietary CadmiumBiotechnologyBiologyProtein markersExcretion

摘要: Because of inherent genetic and physiological characteristics, the natural concentration cadmium in kernels sunflowers grown uncontaminated soils northern Great Plains region United States is higher than most other grains. We tested hypothesis that a habitual consumption sunflower will increase body burden health effects humans. Sixty-six men women who reported consuming various amounts were recruited divided by sex kernel consumption: those consumed less or equal to 1 ounce(oz)/week more oz/week. Cadmium intake was assessed calculation from 7-day food diaries, whole blood cadmium, red cell (RBC) urine concentrations, urinary excretion N-acetyl-beta-D-glucosaminidase (NAG) activity beta2-microglobulin (beta2MG). The results showed high intakes (>1 oz/day) significantly increased (p 0.05). normal ranges for these protein markers have not been established, it possible determine if elevated values meaningful. However, given knowledge with concentrations products average dietary potential exists an cadmium. Controlled feeding studies humans should be pursued order does indeed and, so, cause concern.

参考文章(23)
Marcia J Gartrell, John C Craun, David S Podrebarac, Ellis L Gunderson, Pesticides, selected elements, and other chemicals in adult total diet samples, October 1980-March 1982. Journal of AOAC International. ,vol. 69, pp. 146- 161 ,(1986) , 10.1093/JAOAC/69.1.146
N. Dance, R.G. Price, W.R. Cattell, J. Lansdell, B. Richards, The excretion of and β-galactosidase by patients with renal disease Clinica Chimica Acta. ,vol. 27, pp. 87- 92 ,(1970) , 10.1016/0009-8981(70)90378-5
Yin‐Ming Li, Rufus L. Chaney, Albert A. Schneiter, Jerry F. Miller, Genotype Variation in Kernel Cadmium Concentration in Sunflower Germplasm under Varying Soil Conditions Crop Science. ,vol. 35, pp. 137- 141 ,(1995) , 10.2135/CROPSCI1995.0011183X003500010025X
G.W. Evans, Patrick F. Majors, W.E. Cornatzer, Mechanism for cadmium and zinc antagonism of copper metabolism Biochemical and Biophysical Research Communications. ,vol. 40, pp. 1142- 1148 ,(1970) , 10.1016/0006-291X(70)90913-7
Ian Bremner, James K. Campbell, THE INFLUENCE OF DIETARY COPPER INTAKE ON THE TOXICITY OF CADMIUM Annals of the New York Academy of Sciences. ,vol. 355, pp. 319- 332 ,(1980) , 10.1111/J.1749-6632.1980.TB21350.X
M Berglund, A Akesson, B Nermell, M Vahter, Intestinal absorption of dietary cadmium in women depends on body iron stores and fiber intake. Environmental Health Perspectives. ,vol. 102, pp. 1058- 1066 ,(1994) , 10.1289/EHP.941021058
A Bernard, N Thielemans, H Roels, R Lauwerys, Association between NAG-B and cadmium in urine with no evidence of a threshold. Occupational and Environmental Medicine. ,vol. 52, pp. 177- 180 ,(1995) , 10.1136/OEM.52.3.177