作者: M. T. Jafari , M. Javaheri
DOI: 10.1021/AC101017M
关键词: Chemical ionization 、 Ion-mobility spectrometry 、 Electrospray ionization 、 Thiocyanate 、 Chloride 、 Chromatography 、 Detection limit 、 Analytical chemistry 、 Mass spectrometry 、 Solvent 、 Chemistry
摘要: This study describes a novel technique for direct analysis of thiocyanate in human saliva using negative electrospray-ion mobility spectrometry (ESI-IMS) and without any considerable sample pretreatment. The ESI-IMS system with nearly complete desolvation cannot be useful salivary because overlapping occurs between the format peak solvent peak. In addition, chloride ions existing produce very broad peak, which has drastically interfering effect on SCN− determination. this study, little change operation conditions apparatus (lowering flow rate drift gas), it was possible to overcome these problems. process decreased lower gas, caused separated completely from other interference peaks such as ions. results obtained proposed methodology provide detection limit 0.003 μg/mL linear dynamic range...