MEDICINES COMPRISING Rho KINASE INHIBITOR
作者： Keiji Yamagami , Takashi Ono , Hiroyuki Satoh , Masayoshi Uehata , Toshio Kawahara
DOI:
关键词: Autoimmune disease 、 Arteriosclerosis 、 Asthma 、 Angina 、 Cerebral function 、 Drug 、 Rho kinase inhibitor 、 Medicine 、 Pharmacology 、 Rho-associated protein kinase
摘要: Novel medicines comprising Rho kinase inhibitors, such as hypertension remedy, angina cerebrovascular twitching inhibitor, asthma premature birth preventive, arteriosclerosis anticancer drug, anti-phlogistic, immunosuppressive, autoimmune disease anti-AIDS contraceptive, digestive infection osteoporosis retinopathy and cerebral function ameliorant; reagents diagnostic agents inhibitors.
google.it 参考文章(23)
Tadamasa Saito, Hiroyuki Sato, Masayoshi Uehata, Masafumi Arita, Hirofumi Okuda, 4-amino(alkyl)cyclohexane-1-carboxamide compound and use thereof ,(1992)
Masao Abe, Tomio Muro, Toshio Seki, Hiroyuki Sato, Jun Inui, Trans-4-amino(alkyl)-1-pyridylcarbamoylcyclohexane compounds and pharmaceutical use thereof ,(1989)
Satoshi Toratani, Nobuyuki Sekine, Toshiaki Katada, Hideyoshi Yokosawa, Production of monoclonal antibodies that inhibit ADP-ribosylation of small GTP-binding proteins catalyzed by Clostridium botulinum ADP-ribosyltransferase C3 FEBS Letters. ,vol. 324, pp. 353- 357 ,(1993) , 10.1016/0014-5793(93)80150-S
Keiji Yoshitomi Phar. Ind.Ltd. Yamagami, Masafumi Yoshitomi Phar. Ind. Ltd. Arita, Tadamasa Yoshitomi Phar. Ind. Ltd. Saitoh, Hiroyuki Yoshitomi Phar. Ind. Ltd. Satoh, Masanori Yoshitomi Phar. Ind.Ltd. Minoguchi, Benzamide compound and medicinal use thereof ,(1995)
K Jalink, E J van Corven, T Hengeveld, N Morii, S Narumiya, W H Moolenaar, Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. Journal of Cell Biology. ,vol. 126, pp. 801- 810 ,(1994) , 10.1083/JCB.126.3.801
D Leonard, M.J. Hart, J.V. Platko, A Eva, W Henzel, T Evans, R.A. Cerione, The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein. Journal of Biological Chemistry. ,vol. 267, pp. 22860- 22868 ,(1992) , 10.1016/S0021-9258(18)50026-0
H Hidaka, R Kobayashi, Pharmacology of Protein Kinase Inhibitors Annual Review of Pharmacology and Toxicology. ,vol. 32, pp. 377- 397 ,(1992) , 10.1146/ANNUREV.PA.32.040192.002113
Taisuke Sugihara, Takanori Sone, Yasuharu Sasaki, Hiroyoshi Hidaka, Isoquinolinesulfonyl derivatives and process for the preparation thereof ,(1982)
Takanori Sone, Hiroyoshi Hidaka, Substituted isoquinolinesulfonyl compounds ,(1985)
Masao Abe, Tomio Muro, Toshio Seki, Hiroyuki Sato, Jun Inui, Trans-4-amino(alkyl)-1-pyridylcarbamoyl-cyclohexane compounds and their medicinal use ,(1988)