Histologic and Ultrastructural Analysis of Regenerated Bone in Maxillary Sinus Augmentation Using a Porcine Bone–Derived Biomaterial

作者: Giovanna Orsini , Antonio Scarano , Maurizio Piattelli , Marcello Piccirilli , Sergio Caputi

DOI: 10.1902/JOP.2006.060181

关键词: HistologyMaxillary sinusAcute Inflammatory InfiltrateUltrastructureBiomaterialChemistryBone regenerationOsteoidMatrix (biology)Pathology

摘要: Background: The purpose of the present study was histologic and ultrastructural evaluation a biomaterial composed cortical pig bone in form granules.Methods: After maxillary sinus augmentation using this biomaterial, 10 specimens were retrieved after 5 months patients biomaterial. processed to be observed under light microscopy (LM) transmission electron (TEM). Histomorphometric measurements presented by means ± standard deviations.Results: LM showed that most particles surrounded newly formed bone. In some areas, osteoid matrix present; however, mainly compact at interface. There no evidence an acute inflammatory infiltrate. 36% 2.8% marrow spaces 38% 1.6%, whereas residual grafted material 31% 1.6%. Under TEM, all phases formation (osteoid matrix, woven, lamellar bone) proximity with particles...

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