Integration of immunogenic activation and immunosuppressive reversion using mitochondrial-respiration-inhibited platelet-mimicking nanoparticles

作者: Xiaoli Mai , Yewei Zhang , Haijian Fan , Weitong Song , Ying Chang

DOI: 10.1016/J.BIOMATERIALS.2019.119699

关键词: Immunogenic cell deathCancer researchReversionPlateletChemistryMetastasisMetforminTumor hypoxiaMyeloid-derived Suppressor CellPhotodynamic therapy

摘要: … to the upregulation of myeloid derived suppressor cell (MDSC) which as a key cell induces … the conduct of MDSC-regulated immunosuppressive pathway. Mitochondria are the energy-…

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