Short- versus long-term antimicrobial treatment for acute hematogenous osteomyelitis of childhood: prospective, randomized trial on 131 culture-positive cases.
作者： Heikki Peltola , Markus Pääkkönen , Pentti Kallio , Markku JT Kallio , Osteomyelitis-Septic Arthritis Study Group
DOI: 10.1097/INF.0B013E3181F55A89
关键词: Randomized controlled trial 、 Antibiotics 、 Osteomyelitis 、 Clindamycin 、 Pharmacotherapy 、 Surgery 、 El Niño 、 Antimicrobial 、 Osteitis 、 Medicine
摘要: Background:Considerable uncertainty exists on the optimal duration of antimicrobials for acute hematogenous osteomyelitis (AHOM) in children. Often they are administered 1 to 2 months, first weeks intravenously, and decompressive surgery is usually added. No prospective, randomized, s
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sci-hub.se 参考文章(34)
I. Uckay, M. Assal, L. Legout, P. Rohner, R. Stern, D. Lew, P. Hoffmeyer, L. Bernard, Recurrent osteomyelitis caused by infection with different bacterial strains without obvious source of reinfection Journal of Clinical Microbiology. ,vol. 44, pp. 1194- 1196 ,(2006) , 10.1128/JCM.44.3.1194-1196.2006
P Rollinson, T Nunn, Haematogenous pyogenic bone and joint sepsis - reducing avoidable morbidity South African Medical Journal. ,vol. 97, pp. 456- 460 ,(2007) , 10.7196/SAMJ.818
D. A. Leigh, Determination of serum and bone concentrations of cephradine and cefuroxime by HPLC in patients undergoing hip and knee joint replacement surgery Journal of Antimicrobial Chemotherapy. ,vol. 23, pp. 877- 883 ,(1989) , 10.1093/JAC/23.6.877
Lauritz B. Dahl, Anne-Lise Høyland, Harald Dramsdahl, Per Ivar Kaaresen, Acute Osteomyelitis in Children: A Population-based Retrospective Study 1965 to 1994 Scandinavian Journal of Infectious Diseases. ,vol. 30, pp. 573- 577 ,(1998) , 10.1080/00365549850161124
A. D. Tice, Risk factors and treatment outcomes in osteomyelitis Journal of Antimicrobial Chemotherapy. ,vol. 51, pp. 1261- 1268 ,(2003) , 10.1093/JAC/DKG186
Heikki Peltola, Markus Pääkkönen, Pentti Kallio, Markku J. T. Kallio, , Prospective, Randomized Trial of 10 Days versus 30 Days of Antimicrobial Treatment, Including a Short-Term Course of Parenteral Therapy, for Childhood Septic Arthritis Clinical Infectious Diseases. ,vol. 48, pp. 1201- 1210 ,(2009) , 10.1086/597582
RA Mollan, J Piggot, Acute osteomyelitis in children Journal of Bone and Joint Surgery-british Volume. ,vol. 59, pp. 2- 7 ,(1977) , 10.1302/0301-620X.59B1.845225
SHELDON L. KAPLAN, EDWARD O. MASON, RALPH D. FEIGIN, Clindamycin versus nafcillin or methicillin in the treatment of Staphylococcus aureus osteomyelitis in children. Southern Medical Journal. ,vol. 75, pp. 138- 142 ,(1982) , 10.1097/00007611-198202000-00005
U Heininger, J Bonhoeffer, B Haeberle, U B Schaad, Diagnosis of acute haematogenous osteomyelitis and septic arthritis: 20 years experience at the University Children's Hospital Basel. Swiss Medical Weekly. ,vol. 131, pp. 575- 581 ,(2001)
Hicks He, A PROPHYLACTIC AGAINST RESPIRATORY INFECTIONS. The Lancet. ,vol. 1, pp. 37- ,(1965)