Immunologische Konsequenzen, Rheuma, Infektionen
作者： Thomas Harrer
DOI: 10.1007/978-3-540-78358-9_14
关键词:
摘要: Die Blockade des Chemokinrezeptors 5 (CCR5) durch kleinmolekulare CCR5-Inhibitoren wie Maraviroc hat neue Moglichkeiten fur die Therapie von CCR5-tropen HI-Viren eroffnet. Da Chemokinrezeptoren eine wichtige Rolle in der Immunantwort spielen, stellt sich naturlich Frage, welche Folgen pharmakologische CCR5 Abwehr Infektionen und Entstehung entzundlichen Erkrankungen haben kann. Ein gutes Verstandnis Chemokin-Chemokinrezeptor-Systems ist daher entscheidend Abschatzung Konsequenzen einer pharmakologischen Intervention.
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