Report of a panel on the relationship between public exposure to pesticides and cancer

作者: Len Ritter ,

DOI: 10.1002/(SICI)1097-0142(19971115)80:10<2019::AID-CNCR21>3.0.CO;2-Z

关键词: Human cancerCancerEnvironmental healthRisk factorPopulationMedicinePesticidePesticide residueIncreased riskPublic health

摘要: BACKGROUND Pesticides, which by their nature are biologically active compounds, continue to raise public concern regarding possible role as important etiologic agents in the development of human cancer. METHODS To examine this potential role, National Cancer Institute Canada convened an Ad Hoc Panel on Pesticides and contribution pesticide exposure, particularly general population, cancer. RESULTS The focused primarily exposure population reviewed a range studies that addressed issues related dietary well incidental home garden uses. In addition, examined regulatory framework exists safeguard from potentially carcinogenic pesticides also some benefits use, including availability abundant low cost supply fresh fruits vegetables strategy overall mitigation cancer risk. CONCLUSIONS The concluded it was not aware any definitive evidence suggest synthetic contribute significantly mortality. The did believe increased intake residues associated with poses risk cancer. further concluded, among other things, tobacco use continues be most preventable cause premature mortality thus is appropriate focus for control strategy. [See editorial pages 1887-8, issue.] 1997; 80:2019-33. © 1997 American Society.

参考文章(56)
Jean A T Pennington, Ellis L Gunderson, History of the Food and Drug Administration's total diet study--1961 to 1987. Journal - Association of Official Analytical Chemists. ,vol. 70, pp. 772- 782 ,(1987) , 10.1093/JAOAC/70.5.772
D. Krewski, Douglas L. Arnold, H. C. Grice, Handbook of in vivo toxicity testing Academic Press. ,(1990)
L Polissar, J S Woods, L S Heuser, B G Kulander, R K Severson, Soft tissue sarcoma and non-Hodgkin's lymphoma in relation to phenoxyherbicide and chlorinated phenol exposure in Western Washington Journal of the National Cancer Institute. ,vol. 78, pp. 899- 910 ,(1987)
Godbold J, Wolff Ms, Falck F, Ricci A, Deckers P, Pesticides and polychlorinated biphenyl residues in human breast lipids and their relation to breast cancer. Archives of Environmental Health. ,vol. 47, pp. 143- 146 ,(1992)
Howard Morrison, David Savitz, Robert Semenciw, Barbara Hulka, Yang Mao, Deirdre Morison, Donald Wigle, Farming and Prostate Cancer Mortality American Journal of Epidemiology. ,vol. 137, pp. 270- 280 ,(1993) , 10.1093/OXFORDJOURNALS.AJE.A116674
Adalberto Donna, Pier-Giacomo Betta, Flavio Robutti, Paolo Crosignani, Franco Berrino, Domenico Bellingeri, Ovarian mesothelial tumors and herbicides: a case-control study Carcinogenesis. ,vol. 5, pp. 941- 942 ,(1984) , 10.1093/CARCIN/5.7.941
B Persson, A M Dahlander, M Fredriksson, H N Brage, C G Ohlson, O Axelson, Malignant lymphomas and occupational exposures. Occupational and Environmental Medicine. ,vol. 46, pp. 516- 520 ,(1989) , 10.1136/OEM.46.8.516
R. Frank, B. S. Clegg, C. Sherman, N. D. Chapman, Triazine and chloroacetamide herbicides in Sydenham River water and municipal drinking water, Dresden, Ontario, Canada, 1981–1987 Archives of Environmental Contamination and Toxicology. ,vol. 19, pp. 319- 324 ,(1990) , 10.1007/BF01054972