Latent state-space models for neural decoding.

作者: Mehdi Aghagolzadeh , Wilson Truccolo

DOI: 10.1109/EMBC.2014.6944262

关键词: PopulationPremovement neuronal activityComputer sciencePattern recognitionPrimary motor cortexMotor cortexKalman filterState spaceDecoding methodsArtificial intelligenceNeural decoding

摘要: Ensembles of single-neurons in motor cortex can show strong low-dimensional collective dynamics. In this study, we explore an approach where neural decoding is applied to estimated dynamics instead the full recorded neuronal population. A latent state-space model (SSM) used estimate from measured spiking activity population neurons. second representation then decode kinematics, via a Kalman filter, The SSM-based illustrated on primary monkey performing naturalistic 3-D reach and grasp movements. Our analysis that performance based comparable

参考文章(6)
Mark M. Churchland, John P. Cunningham, Matthew T. Kaufman, Justin D. Foster, Paul Nuyujukian, Stephen I. Ryu, Krishna V. Shenoy, Neural population dynamics during reaching Nature. ,vol. 487, pp. 51- 56 ,(2012) , 10.1038/NATURE11129
Arjun K. Bansal, Wilson Truccolo, Carlos E. Vargas-Irwin, John P. Donoghue, Decoding 3D reach and grasp from hybrid signals in motor and premotor cortices: spikes, multiunit activity, and local field potentials Journal of Neurophysiology. ,vol. 107, pp. 1337- 1355 ,(2012) , 10.1152/JN.00781.2011
Arjun K. Bansal, Carlos E. Vargas-Irwin, Wilson Truccolo, John P. Donoghue, Relationships among low-frequency local field potentials, spiking activity, and three-dimensional reach and grasp kinematics in primary motor and ventral premotor cortices. Journal of Neurophysiology. ,vol. 105, pp. 1603- 1619 ,(2011) , 10.1152/JN.00532.2010
Wilson Truccolo, Leigh R Hochberg, John P Donoghue, Collective dynamics in human and monkey sensorimotor cortex: predicting single neuron spikes Nature Neuroscience. ,vol. 13, pp. 105- 111 ,(2010) , 10.1038/NN.2455
Sam Roweis, Zoubin Ghahramani, None, A unifying review of linear Gaussian models Neural Computation. ,vol. 11, pp. 305- 345 ,(1999) , 10.1162/089976699300016674