A preparation of haloalkylidene cyclopentanones
作者： Nicholas J. Cornwall , Shaun Linehan , Rex T. Weavers
DOI: 10.1016/S0040-4039(97)00503-0
关键词: Double bond 、 Ketone 、 Organic chemistry 、 Stereoselectivity 、 Degree (temperature) 、 Chemistry
摘要: A radical-based 5-exo-dig cyclisation, initiated by addition of a trichloromethyl radical to an acyclic acetylenic ketone with appropriately positioned double bond, has been employed produce variety cyclic haloalkylidene cyclopentanones in moderate excellent yields and high degree stereoselectivity for the (E)-isomer.
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