New analgesic and nootropic drugs
作者： Carla Ghelardini , Gino Toffano , Alberto Giotti , Fulvio Gualtieri , Alessandro Bartolini
DOI:
关键词: Para position 、 Analgesic 、 Nootropic 、 Nootropic Drugs 、 Stereochemistry 、 Analgesic effect 、 Learning facilitation 、 Enantiomer 、 Chemistry
摘要: Compounds of general formula (I), where Ar = phenyl or beta-naphtyl, R1 one more substituents the beta-naphtyl nucleus, preferably in para position, and selected out group consisting H, CH3, C(CH3)3, CH2-CH-(CH3)2, O-CH3, C1, F, Br, CF3, NH2, S-CH3, SO-CH3, CN, NO2; R2 C2H5, CH(CH3)2, CH2OH, C6H5; R3 (a); R4 CH2-C6H5; R5 CH3; X none O, S, NH, NCH3; Y both racemic form isomeric enantiomeric forms, which produce a nootropic effect, i.e. memory enhancement learning facilitation, as well an analgesic effect.
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