Rapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case Study.

作者: James L. J. Coleman , Karen Brennan , Tony Ngo , Poornima Balaji , Robert M. Graham

DOI: 10.3389/FENDO.2015.00105

关键词: Conditional gene knockoutInternational Knockout Mouse ConsortiumGene knockoutCre recombinaseKnockout mouseTransgeneBiologyGeneticsGenetically modified mouseKnockout rat

摘要: … our desire to generate inducible, tissue-specific knockout mice so that we could explore the … One such conditional model is the cardiomyocyte-specific deletion of our GOIs by crossing …

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