Relation of body weight to development of coronary heart disease. The Framingham study.

作者: WILLIAM B. KANNEL , E. JOSEPH LEBAUER , THOMAS R. DAWBER , PATRICIA M. MCNAMARA

DOI: 10.1161/01.CIR.35.4.734

关键词: Framingham Risk ScoreWeight changeObesityBlood pressureFramingham Heart StudySudden deathMedicineInternal medicineCardiologyMyocardial infarctionAngina

摘要: Interrelationships between weight change, serum cholesterol, blood pressure levels, and the risk of developing coronary heart disease have been explored in 5,127 men women who followed over 12 years for signs initial development disease. Antecedent relative gain after age 25 proved to be strongly related angina pectoris sudden death but were unassociated with myocardial infarction. An excess appeared exist obese both without elevations indicating an independent contribution obesity rate these manifestations Unless accompanied by increase cholesterol level, play a negligible role women. Subjects predisposing factors had pronounced risk, greater than that associated e...

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