Ghrelin and the metabolic balance
作者： O. Ukkola
DOI: 10.1007/BF03347580
关键词: Energy metabolism 、 Ghrelin 、 Future studies 、 Hormone 、 Chemistry 、 Endocrinology 、 Internal medicine 、 Adipose tissue metabolism 、 Energy balance 、 Metabolic balance 、 Insulin metabolism
摘要: Several studies have provided evidence that ghrelin is involved in the regulation of metabolic balance. Recent data provide when studying effects on energy balance, differential influences acylated and non-acylated forms peptide must be considered. Although correlation between two good, they may different hormones with opposite actions being able to antagonize some form. Future will reveal which ghrelin, or forms, dominates determines net influence
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T. Østergård, T. Hansen, B. Nyholm, C. Gravholt, C. Djurhuus, H. Hosoda, K. Kangawa, O. Schmitz, Circulating ghrelin concentrations are reduced in healthy offspring of Type 2 diabetic subjects, and are increased in women independent of a family history of Type 2 diabetes. Diabetologia. ,vol. 46, pp. 134- 136 ,(2003) , 10.1007/S00125-002-0985-4
Matthias Tschöp, David L. Smiley, Mark L. Heiman, Ghrelin induces adiposity in rodents. Nature. ,vol. 407, pp. 908- 913 ,(2000) , 10.1038/35038090
S. Pöykkö, O. Ukkola, H. Kauma, M. J. Savolainen, Y. A. Kesäniemi, Ghrelin Arg51Gln mutation is a risk factor for Type 2 diabetes and hypertension in a random sample of middle-aged subjects Diabetologia. ,vol. 46, pp. 455- 458 ,(2003) , 10.1007/S00125-003-1058-Z
Kazuhiko Takaya, Hiroshi Iwakura, Hiroshi Hosoda, Takashi Akamizu, Yuji Arai, Kenji Kangawa, Kazuwa Nakao, Hiroyuki Ariyasu, Transgenic Mice Overexpressing Des-Acyl Ghrelin Show Small Phenotype Endocrinology. ,vol. 146, pp. 355- 364 ,(2005) , 10.1210/EN.2004-0629
Paolo Marzullo, Barbara Verti, Giulio Savia, Gillian E. Walker, Gabriele Guzzaloni, Mariantonella Tagliaferri, Annamaria Di Blasio, Antonio Liuzzi, The relationship between active ghrelin levels and human obesity involves alterations in resting energy expenditure. The Journal of Clinical Endocrinology and Metabolism. ,vol. 89, pp. 936- 939 ,(2004) , 10.1210/JC.2003-031328
Matthias Möhlig, J. Spranger, B. Otto, M. Ristow, M. Tschöp, A. F. H. Pfeiffer, Euglycemic hyperinsulinemia, but not lipid infusion, decreases circulating ghrelin levels in humans Journal of Endocrinological Investigation. ,vol. 25, ,(2002) , 10.1007/BF03344062
Olavi Ukkola, Eric Ravussin, Peter Jacobson, Eric E. Snyder, Monique Chagnon, Lars Sjöström, Claude Bouchard, RAPID COMMUNICATIONS: Mutations in the Preproghrelin/Ghrelin Gene Associated with Obesity in Humans The Journal of Clinical Endocrinology and Metabolism. ,vol. 86, pp. 3996- 3999 ,(2001) , 10.1210/JCEM.86.8.7914
C. Holdstock, J. Ludvigsson, F. A. Karlsson, Abnormal ghrelin secretion in new onset childhood Type 1 diabetes. Diabetologia. ,vol. 47, pp. 150- 151 ,(2004) , 10.1007/S00125-003-1258-6
C. Gauna, F. M. Meyler, J. A. M. J. L. Janssen, P. J. D. Delhanty, T. Abribat, P. van Koetsveld, L. J. Hofland, F. Broglio, E. Ghigo, A. J. van der Lely, Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity. The Journal of Clinical Endocrinology and Metabolism. ,vol. 89, pp. 5035- 5042 ,(2004) , 10.1210/JC.2004-0363
Mohammed F. Saad, Basem Bernaba, Chii-Min Hwu, Sujata Jinagouda, Salwa Fahmi, Ella Kogosov, Rima Boyadjian, Insulin Regulates Plasma Ghrelin Concentration The Journal of Clinical Endocrinology and Metabolism. ,vol. 87, pp. 3997- 4000 ,(2002) , 10.1210/JCEM.87.8.8879