Human Endothelial Cell Models in Biomaterial Research

摘要: Endothelial cell (EC) models have evolved as important tools in biomaterial research due to ubiquitously occurring interactions between implanted materials and the endothelium. However, screening available literature has revealed a gap material scientists physiologists terms of their understanding these biomaterial–endothelium relative importance. Consequently, EC are often applied nonphysiological experimental setups, or too extensive conclusions drawn from results. The question arises whether this might be one reason why, among many potential biomaterials, only few found way into clinic. In review, we provide an overview established possible selection criteria enable researchers determine most reliable relevant model use.