Prevalences of the Enterobacter cloacae complex and its phylogenetic derivatives in the nosocomial environment.

作者: A. Kremer , H. Hoffmann

DOI: 10.1007/S10096-012-1646-2

关键词: Medical microbiologyPhylogenetic treeMicrobiologyCladeOutbreakPulsed-field gel electrophoresisGenotypeBiologyBlood cultureSubspecies

摘要: Despite the importance of Enterobacter cloacae complex as a nosocomial pathogen, little is known about relative contribution its single species and genotypes to pathogenicity. We studied here relationship between phylogenetically related strains clinical infection sites. A total 196 prospectively collected isolates E. were included in study, comprising 67 blood culture isolates. Isolates analyzed for clonality by pulsed-field gel electrophoresis (PFGE) genetically assigned their partial hsp60 sequencing. Most belonged phylogenetic clade 1, with hormaechei being most prevalent species. Notably, some species, indeed, showed predilections certain specimens, whereas outbreaks members rare. Our study stresses need identify alleged on subspecies level routine order obtain more insight into distinct infectious potentials.

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