Irinotecan as salvage chemotherapy for advanced small bowel adenocarcinoma: a series of three patients.

摘要: Abstract Small bowel adenocarcinoma (SBA) is a relatively rare disease. Because of its rarity the role chemotherapy either as adjuvant or for advanced disease has not been clearly defined. Therefore any information, including case reports, warranted. We report on three patients with jejunum and ileum. Two positive lymph nodes received postoperative 5-fluorouracil-folinic acid (5FU-FA) 12 months but they developed metastatic 3 8 later, respectively. The third patient was initially treated same agents All were subsequently tumor recurrence irinotecan 350mg/m2 i.v. every weeks salvage supported by Granulocyte Colony Stimulating Factor (GCSF) 5 days. achieved minor response had dramatic improvement their symptoms. Their survival times after administration 14 6 an overall ...