Polynucleotides. V. Titration and spectrophotometric studies upon the interaction of synthetic polynucleotides with various dyes

作者: R.F. Steiner , R.F. Beers

DOI: 10.1016/0003-9861(59)90177-8

关键词: PolynucleotideTitrationAcridine orangePhotochemistryPolymerMethylene blueUltraviolet absorptionMonomerChemistry

摘要: Abstract The dyes acridine orange and methylene blue have been found to undergo a striking change in visible ultraviolet absorption spectra the presence of polyriboadenylic acid polyribocytidylic acid. This reaction does not occur with corresponding monomers. In case acid, binding appears inhibit structural this polymer at pH's.

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