Stable Isotopes of Minerals as Metabolic Tracers in Human Nutrition Research

摘要: Enriched stable isotopes used as tracers have proven to be valuable in studies of the absorption and metabolism minerals. Unlike radioisotopes, they can high-risk population groups such infants, children, pregnant or lactating women. Estimates mineral made from oral administration a single tracer two tracers, one given orally other intravenously (IV). It is possible determine with modeling based on amount different biological samples. One key decisions this type determining which enriched isotope what use. An example calculations estimate compare amounts needed for an study. Methods calculating IV doses are presented, limits detection quantitation discussed terms percent enrichment related ratio measurement precision. A ...