How Iron Activates O2

摘要: Iron enzymes play a key role in many biological processes involving oxygen, from the biosynthesis of DNA to conversion electrochemical chemical energy. In her Perspective, Kovacs highlights two reports that shed light on some intermediates may be involved reactions promoted by nonheme iron enzymes. Rohde et al. study analog system, while Karlsson investigate enzyme naphthalene dioxygenase with x-ray crystallography. By catching fleeting intermediates, studies help understand enzymatic mechanism this important group proteins.