Early Treatment Response in Malignant Lymphoma, As Determined by Planar Fluorine-18-Fluorodeoxyglucose Scintigraphy

摘要: Clinical oncology needs flexible techniques for routine monitoring of treatment response. We therefore compared planar 18F-fluorodeoxyglucose (FDG) with a conventional gamma-camera and special collimator to 67Ga scintigraphy in 26 patients malignant lymphoma during chemotherapy. The scintigraphic appearance involved sites was essentially the same both tracers: eventually achieving complete remission, tracer distribution had normalized after two courses; high uptake reflected failure; faint associated variable outcome. For (re)staging, may be preferable (higher contrast). To document initial response, we performed FDG first course (n = 11). Effective sharply reduced metabolic tumor activity within days prior volume whereas abnormal persisted failure. Planar tool assess potentially prognostic response rate, preventing over-treatment allowing timely switch more aggressive therapy.