Estrogen modulates neural-immune interactions through intracellular signaling pathways and antioxidant enzyme activity in the spleen of middle-aged ovariectomized female rats.

作者: Prathamesh Kale , Aparna Mohanty , Anushree Patil , Miti Mishra , Uday P. Pratap

DOI: 10.1016/J.JNEUROIM.2013.11.003

关键词: Ovariectomized ratEndocrinologyNerve growth factorChemistryEstrogenSuperoxide dismutaseTyrosine hydroxylaseLipid peroxidationProtein kinase BInternal medicineCREB

摘要: … 0.6 μg of 17β-estradiol significantly (p < 0.001) decreased con A-induced IL-2 production while no significant change in its level was observed in rats treated with 300 μg of 17β-estradiol …

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