The Role of Domestic Allergens

摘要: The documented increase in asthma has been almost entirely perennial and a large proportion of the cases are allergic to one common allergens found all year round houses, i.e. house dust mites, cats, dogs or cockroaches. In population case-control studies sensitization these is strongest risk factor for (adjusted odds ratios > = 4). Using monoclonal antibody-based assays major indoor it shown that mites directly related concentration Group 1 mite allergen dust. This led hypothesis increases secondary changes houses were responsible asthma. However, also increased areas world where do not flourish. dry other Although asthmatics reflects their measurements exposure accurately predict severity symptoms. Other factors can contribute symptoms may have increased. particular, diesel particulates, ozone, beta 2-agonists, endotoxin rhinovirus infection each enhance inflammatory response inhaled allergens. Increases must relate some aspect our predominantly sedentary lifestyle; this could be either an lungs foreign proteins.