Membrane-destabilizing polyanions: interaction with lipid bilayers and endosomal escape of biomacromolecules.

作者: Marie-Andrée Yessine , Jean-Christophe Leroux

DOI: 10.1016/J.ADDR.2003.10.039

关键词: Drug deliveryOrganic chemistryConformational changeMembraneBiophysicsPolyelectrolyteBiological membraneBiomoleculeLipid bilayerMacromolecular SubstancesChemistry

摘要: Water-soluble synthetic polyanions are employed nowadays … Recently, polyanions have been evaluated as part of drug … of pH-responsive synthetic polyanions in drug delivery. The pH-…

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