Cancer-specific MALDI-TOF profiles of blood serum and plasma: biological meaning and perspectives.
作者： M.A. Karpova , S.A. Moshkovskii , I.Y. Toropygin , A.I. Archakov
DOI: 10.1016/J.JPROT.2009.09.011
关键词: Biomarker discovery 、 Chemistry 、 Biomarker (cell) 、 Proteases 、 Acute-phase protein 、 Matrix-assisted laser desorption/ionization 、 Blood serum 、 Blood proteins 、 Biochemistry 、 Blood plasma
摘要: MALDI-TOF mass-spectrometry has become a popular tool of cancer research during the last decade. High throughput and relative simplicity this technology have made it attractive for biomarker discovery validation across various platforms in blood serum/plasma. Many technical approaches been developed plasma/serum profiling including protein-chip based SELDI-TOF mass-spectrometry, purification serum on magnetic beads, analysis carrier-associated fraction mass-spectrometric immunoassays. Extensive data about identity differential features detected mass-spectra up to now makes possible draw conclusions potency perspectives field. A great majority identified differentially expressed proteins are either house-keeping or inflammatory as well their modifications fragments. Discriminating ability is likely be modification fragmentation patterns abundant reflecting activity enzymes proteases inhibitors.
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sci-hub.se 参考文章(148)
Fatin K Al-Hindawi, Nabil A Bashir, Zeyad J El-Akawi, Alpha-1 antitrypsin (alpha1-AT) plasma levels in lung, prostate and breast cancer patients. Neuro endocrinology letters. ,vol. 29, pp. 482- 484 ,(2008)
Li-Yun Liu, Ji-Fu Liu, Xue-Yuan Xiao, Song-Wei Dai, Shuan-Ying Yang, Xiao-Min Wang, Li-Juan Zhang, Shan-Shan Wu, Sam Fu, Dan-Hui Liu, Da-Cheng He, Serum amyloid A protein: a potential biomarker correlated with clinical stage of lung cancer. Biomedical and Environmental Sciences. ,vol. 20, pp. 33- 40 ,(2007)
Seth Rakoff-Nahoum, Why cancer and inflammation Yale Journal of Biology and Medicine. ,vol. 79, pp. 123- 130 ,(2006)
Wei-Min Gao, Rork Kuick, Randal P Orchekowski, David E Misek, Ji Qiu, Alissa K Greenberg, William N Rom, Dean E Brenner, Gilbert S Omenn, Brian B Haab, Samir M Hanash, Distinctive serum protein profiles involving abundant proteins in lung cancer patients based upon antibody microarray analysis BMC Cancer. ,vol. 5, pp. 110- 110 ,(2005) , 10.1186/1471-2407-5-110
K. Annecke, M. Schmitt, U. Euler, M. Zerm, D. Paepke, S. Paepke, G. von Minckwitz, C. Thomssen, N. Harbeck, uPA AND PAI-1 In Breast Cancer: Review Of Their Clinical Utility And Current Validation In The ProspectivE NNBC-3 TRIAL Advances in Clinical Chemistry. ,vol. 45, pp. 31- 45 ,(2008) , 10.1016/S0065-2423(07)00002-9
Etzioni Ruth, Urban Nicole, Ramsey Scott, M Martin, Schwartz Stephen, Reid Brian, Radich Jerald, Anderson Garnet, Hartwell Leland, THE CASE FOR EARLY DETECTION Nature Reviews Cancer. ,vol. 3, pp. 243- 252 ,(2003) , 10.1038/NRC1041
Lori J. Sokoll, Jason Rosenzweig, Daniel W. Chan, Eric T. Fung, Ie-ming Shih, Zhen Zhang, Thang Pham, Alex J. Rai, Proteomic approaches to tumor marker discovery. Archives of Pathology & Laboratory Medicine. ,vol. 126, pp. 1518- 1526 ,(2002) , 10.5858/2002-126-1518-PATTMD
R W Mahley, T L Innerarity, S C Rall, K H Weisgraber, Plasma lipoproteins: apolipoprotein structure and function. Journal of Lipid Research. ,vol. 25, pp. 1277- 1294 ,(1984) , 10.1016/S0022-2275(20)34443-6
Janko Kos, Borut S̆tabuc, Nina Cimerman, Nils Brünner, Serum Cystatin C, a New Marker of Glomerular Filtration Rate, Is Increased during Malignant Progression Clinical Chemistry. ,vol. 44, pp. 2556- 2557 ,(1998) , 10.1093/CLINCHEM/44.12.2556
Jinong Li, Rosaria Orlandi, C Nicole White, Jason Rosenzweig, Jing Zhao, Ettore Seregni, Daniele Morelli, Yinhua Yu, Xiao-Ying Meng, Zhen Zhang, Nancy E Davidson, Eric T Fung, Daniel W Chan, Independent Validation of Candidate Breast Cancer Serum Biomarkers Identified by Mass Spectrometry Clinical Chemistry. ,vol. 51, pp. 2229- 2235 ,(2005) , 10.1373/CLINCHEM.2005.052878