Alterations of serotonin transmission in schizophrenia.
DOI: 10.1016/S0074-7742(06)78005-9
关键词: Serotonergic 、 Schizophrenia 、 Dopamine 、 Pathophysiology 、 Neuroscience 、 Psychology 、 Serotonin metabolism 、 Serotonin 、 Serotonergic Agonists
摘要: A role for serotonin alterations in the pathophysiology of schizophrenia has long been suspected because psychotogenic effects serotonergic agonists and therapeutic 5-HT(2) antagonism. This chapter is a review evidence derived from pharmacological studies, postmortem, imaging studies that have assessed transmission schizophrenia. While clear picture specific not emerged despite much research, this reinforces modulatory agents on dopamine schizophrenia, which may contribute to atypical antipsychotics.
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