Source Specific Risk Assessment of Indoor Aerosol Particles

摘要: In the urban environment, atmospheric aerosols consist mainly of pollutants from anthropogenic sources. The majority these originate traffic and other combustion processes. A fraction will penetrate indoors via ventilation. However, indoor air concentrations are usually predominated by sources due to small amount dilution air. modern societies, people spend most their time indoors. Thus, exposure is controlled During last decades, engineering nanosized structures has created a new field material science. Some materials have been shown be potentially toxic human health. greatest potential for engineered nanomaterials (ENMs) occurs in workplace during production handling ENMs. an assessment, both gaseous particulate matter need considered. toxicities particles depend on source age. With time, particle morphology composition changes tendency undergo coagulation, condensation evaporation. PM risk related specific emissions, thus, assessment one needs define exposures. This thesis describes methods airborne matter. It consists studies workers’ ENM exposures synthesis nanoparticles, packing agglomerated TiO2 nanodiamonds. Background were distinguished using different measurement techniques aerosol modelings. Risk characterization was performed calculated dose levels units number mass. estimated non-health based occupational limits For TiO2, also assessed dose-biological responses which had extrapolated inhalation conducted mice. compared with background order determine relevant metrics scenarios.