Mechanisms in Interleukin 3 Regulated Growth and Differentiation

作者: James N. Ihle , Yacob Weinstein , Ulf R. Rapp , John L. Cleveland , E. Premkumar Reddy

DOI: 10.1007/978-1-4684-5323-2_15

关键词: Interleukin 20Cell biologyLymphokineInterleukin 3MyeloidHaematopoiesisBiologyCell typeColony-stimulating factorImmune system

摘要: The immune system regulates the growth and differentiation of a variety hematopoietic lymphoid lineages through production series lymphokines by activated T cells. Among these interleukin-2 (IL-2) has been most extensively studied shown to support proliferation major colony stimulating factor produced cells, granulocyte-macrophage (GM-CSF), supports terminal cells committed myeloid lineage. B-cell (BSF-1) B may induce additional cell types. In contrast factors, which primarily act on mature interleukin-3 (IL-3) acts relatively immature hematopoietic/lymphoid

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