Elimination of Botulinum Neurotoxin (BoNT) Type B from Drinking Water by Small-Scale (Personal-Use) Water Purification Devices and Detection of BoNT in Water Samples
作者： Ari Hörman , Mari Nevas , Miia Lindström , Marja-Liisa Hänninen , Hannu Korkeala
DOI: 10.1128/AEM.71.4.1941-1945.2005
关键词: Toxin 、 Chromatography 、 Purified water 、 Reverse osmosis 、 Water treatment 、 Effluent 、 Clostridium botulinum 、 Portable water purification 、 Raw water 、 Chemistry
摘要: Seven small-scale drinking water purification devices were evaluated for their capacity to eliminate botulinum neurotoxin (BoNT) type B from water. Influent inoculated with toxic Clostridium cultures and effluent purified samples tested the presence of BoNT by using a standard mouse bioassay two commercial rapid enzyme immunoassays (EIAs). The based on filtration through ceramic or membrane filters pore size 0.2 0.4 m irradiation low-pressure UV-lamp (254 nm) failed remove raw (reduction 2.3 log10 units). EIAs intended detection various types detect aqueous containing an estimated concentration 396,000 ng/liter.
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