Effects of in vitro culture at the preimplantation embryo stage on early development and hypertension in ISIAH rats.
作者： Tatyana N. Igonina , Diana S. Ragaeva , Olga M. Petrova , Irina N. Rozkova , Eugeny Yu. Brusentsev
DOI: 10.1080/10641955.2019.1647232
关键词: Andrology 、 Blood pressure 、 In vitro 、 Offspring 、 Phenotype 、 Embryo transfer 、 Embryo stage 、 Medicine
摘要: Objective: The study investigates how IVC and ET affect hypertensive phenotype in ISIAH rats. Methods: rats born as the result of were compared with naturally conceived controls. Results: Embryo transfer from to normotensive recipient dams caused lower SBP DBP female offspring. When was accompanied vitro culture R1ECM, not only offspring, but also males demonstrated alleviation hypertension. Conclusions: at preimplantation embryo stage affected manifestation hypertension adult
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