Receptor heterodimerization leads to a switch in signaling: β-arrestin2-mediated ERK activation by μ-δ opioid receptor heterodimers

作者: Raphael Rozenfeld , Lakshmi A. Devi

DOI: 10.1096/FJ.06-7793COM

关键词: μ-opioid receptorBeta-ArrestinsCell biologyReceptorPharmacologyOpioid receptorReceptor complexDAMGOSignal transductionBiologyG protein-coupled receptor

摘要: … examined heterodimer-mediated ERK phosphorylation and … complexes that include G-proteins, scaffolding molecules (such as β-… of events involving G-protein activation, a component of …

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