作者: Roel Van Holen , Karel Deprez , Stefaan Vandenberghe
DOI:
关键词: Lyso- 、 Optics 、 Nuclear medicine 、 Image resolution 、 Field of view 、 Physics 、 Detector 、 Stopping power 、 Calibration 、 Scintillator 、 Resolution (electron density)
摘要: 2159 Objectives We have previously reported on the design of a NaI(Tl) based SPECT detector. The 5 mm thick scintillator resulted in large light spread and sampling capability Position Sensitive Photomultiplier (PSPMT) was not fully exploited. LYSO is an interesting alternative as it has higher stopping power. In order to improve spatial resolution we investigate performance 2 continuous scintillator. Methods coupled 49 x H8500 PSPMT. energy measured by directing 140 KeV (Tc99m) beam source center detector calibrated scanning its surface with 1 grid; mean response function (MDRF) calculated for each grid point. Interpolation used obtain MDRFs 250 μm grid. To measure resolution, performed 5.5 scan source. acquired events were positioned using nearest neighbor search calibration data. intrinsic activity performing blank acquisition 600 s. Results 20.4%. Ten percent photo-electric do deposit their full scintillator: this due characteristic X-ray escape. If take that are lost escape into account, then detection efficiency 2mm (73.7 %) still larger than (64.2 %). 1.04 field view 0.94 central view, compared 1.68 1.29 NaI(Tl). radio-activity low (0.02 cps / mm^3) 112 168 window. Conclusions worse more uniform better problematic acquisitions. Research Support This research funded EU FP7 project SUBLIMA (Grant Agreement No. 241711), IOF-Flanders iMinds. Roel Van Holen Foundation- Flanders (FWO, Belgium) Ghent University.