Hepatitis B: Resistência a Análogos Núcleos(t)idos Hepatitis B: Resistência a Análogos Núcleos(t)idos Hepatitis B: Resistência a Análogos Núcleos(t)idos Hepatitis B: Resistência a Análogos Núcleos(t)idos Hepatitis B: Resistência a Análogos Núcleos(t)idos Hepatitis B: Resistance to Nucleosideos Analogues

作者: Hugo Fainboim , Silvia Paz

DOI:

关键词: VirusLamivudineHepatitis BEmtricitabinaAdefovirTenofovirEntecavirVirologyMedicineInterferon

摘要: A infeccao pelo virus B e um importante problema de saude publica. E a causa mais frequente cirrose hepatocarcinoma no mundo. As drogas utilizadas tratamento da hepatite cronica (HBV) sao : Interferon peguilado (IFN-PEG), lamivudina (LMV), adefovir dipivoxil (ADV) entecavir (ETV). Outras se encontram em investigacao:telbivudina (LdT), emtricitabina (FTC), tenofovir (TDF) clevudina (CVD). resistencia ao comun com os analogos nucleotideos, sendo principal dstes. O estudo novas combinacoes fundamental para evitar esta atingir erradiccao viral. Palavras-chave: B, viral, lamivudina. The infection is un important health problem. It the most frequent cause of cirrhosis and celular in world. used drugs for treating hepatitis ar: peguilated interferon, lamivudine, entecavir. Others are still investigation phase. resistance common with lamivudine. New therapy combination essential avoiding this resistency obtaining viral clearance.

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